鯤羽生物經(jīng)過多年研發(fā)、創(chuàng)新和沉淀，在科服板塊已建立、完善多條技術(shù)產(chǎn)品線，包括高分辨單細(xì)胞基因原位雜交、空間轉(zhuǎn)錄組測序、空間基因組和單細(xì)胞圖譜等。近期鯤羽生物已助力客戶在Cell、Nat Genet、Neuron、Nat Plants、Dev cell、Nat Commun、Sci Adv、Elife 等國際一流期刊發(fā)表重要論文多篇，涉及神經(jīng)科學(xué)、遺傳學(xué)、表觀組學(xué)、植物學(xué)、腫瘤病理等多個學(xué)科領(lǐng)域，在技術(shù)層面助力科學(xué)家解決關(guān)鍵難題，解鎖重要科學(xué)現(xiàn)象，推動科學(xué)領(lǐng)域重大發(fā)現(xiàn)。這一系列研究成果在國際雜志的發(fā)表標(biāo)志著鯤羽生物走向國際、服務(wù)全球！
鯤羽生物一直秉持真誠、嚴(yán)謹(jǐn)、科學(xué)的態(tài)度，秉承助力科學(xué)探索、普惠百姓健康、崇尚科技創(chuàng)新、立足產(chǎn)業(yè)興國的理念，在技術(shù)上不斷尋求突破創(chuàng)新，持續(xù)為全球科學(xué)研究和技術(shù)發(fā)展貢獻全力。公司也在努力為大家提供更好的產(chǎn)品與服務(wù)，推動民族生物原始技術(shù)創(chuàng)新走向世界、服務(wù)全球！
文章詳情：
Xiaoqian Liu, Zunpeng Liu, Zeming Wu, Jie Ren et al.,Resurrection of endogenous retroviruses during aging reinforces senescence. Cell.2023.
Yu J, Xiao K, Chen X, Deng L, Zhang L, Li Y, Gao A, Gao J, Wu C, Yang X, Zhou Q, Yang J, Bao C, Jiao J, Cheng S, Guo Z, Xu W, Cao X, Guo Z, Dai J, Hu J, Fu Z, Cao G. Neuron-derived neuropeptide Y fine-tunes the splenic immune responses. Neuron. 2022.Xu Z, Feng Z, Zhao M, Sun Q, Deng L, Jia X, Jiang T, Luo P, Chen W, Tudi A, Yuan J, Li X, Gong H, Luo Q, Li A. Whole-brain connectivity atlas of glutamatergic and GABAergic neurons in the mouse dorsal and median raphe nuclei. Elife. 2021.Xiao Q, Huang X, Zhang Y, Xu W, Yang Y, Zhang Q, Hu Z, Xing F, Sun Q, Li G, Li X. The landscape of promoter-centred RNA-DNA interactions in rice. Nat Plants. 2022.Liu Z, Ji Q, Ren J, Yan P, Wu Z, Wang S, Sun L, Wang Z, Li J, Sun G, Liang C, Sun R, Zhao G, Wang H, Zhou Q, Belmonte JCI, Qu J, Zhang W, Liu G. Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging. Dev Cell. 2022.Xiao K, Xiong D, Chen G, Yu J, Li Y, Chen K, Zhang L, Xu Y, Xu Q, Huang X, Gao A, Cao K, Yan K, Dai J, Hu X, Ruan Y, Fu Z, Li G, Cao G. RUNX1-mediated alphaherpesvirus-host trans-species chromatin interaction promotes viral transcription. Sci Adv. 2021.Lin D, Hong P, Zhang S, Xu W, Jamal M, Yan K, Lei Y, Li L, Ruan Y, Fu ZF, Li G, Cao G. Digestion-ligation-only Hi-C is an efficient and cost-effective method for chromosome conformation capture. Nat Genet. 2018.Yonghao Sun, Liang Dong, Ying Zhang, Da Lin, Weize XuChangxiong Ke, Linqian Han, Guoliang Li, David Jackson, Xingwang Li, Fang Yang. 3D genome architecture coordinates trans and cis regulation of differentially expressed ear and tassel genes in maize. Genome Biology, 2020.Canhui Cao, Ping Hong, Xingyu Huang, Da Lin, Gang Cao, Liming Wang, Bei Feng, Ping Wu, Hui Shen, Qian Xu, Ci Ren, Yifan Meng, Wenhua Zhi, Ruidi Yu, Juncheng Wei, Wencheng Ding, Xun Tian, Qinghua Zhang, Wei Li, Qinglei Gao, Gang Chen, Kezhen Li, Wing- Kin Sung, Zheng Hu, Hui Wang, Guoliang Li, Peng Wu. HPV CCDC106 Integration Alters Local Chromosome Architecture and Hijacks an Enhancer by Remodeling the 3D Genome Structure in Cervical Cancer. Journal of Genetics and Genomics, 2020.Lin D, Xu W, Hong P, Wu C, Zhang Z, Zhang S, Xing L, Yang B, Zhou W, Xiao Q, Wang J, Wang C, He Y, Chen X, Cao X, Man J, Reheman A, Wu X, Hao X, Hu Z, Chen C, Cao Z, Yin R, Fu ZF, Zhou R, Teng Z, Li G, Cao G. Decoding the spatial chromatin organization and dynamic epigenetic landscapes of macrophage cells during differentiation and immune activation. Nat Commun. 2022.鯤羽生物團隊擁有20余年基因原位雜交和10年空間組學(xué)研發(fā)經(jīng)驗，專注于高靈敏度、高檢測效率、單細(xì)胞精度、多基因的原位雜交技術(shù)和原位測序空間組學(xué)技術(shù)的研發(fā)與應(yīng)用， 自主研發(fā)了高特異性、高分辨率新型原位雜交檢測技術(shù)和空間多組學(xué)原位測序技術(shù)，提供從單細(xì)胞測序到基因原位檢測、空間多維組學(xué)一站式解決方案及相關(guān)臨床診斷產(chǎn)品，滿足基礎(chǔ)科研與臨床應(yīng)用需求。
18202735305
spatialfish@spatialfish.com
深圳光明國家級高新區(qū)、江門新會國家級高新區(qū)
